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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFBR2
All Species:
31.82
Human Site:
Y281
Identified Species:
63.64
UniProt:
P37173
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P37173
NP_001020018.1
567
64568
Y281
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Chimpanzee
Pan troglodytes
XP_001166587
603
68631
Y317
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Rhesus Macaque
Macaca mulatta
XP_001095987
567
64487
Y281
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Dog
Lupus familis
XP_534237
569
64614
Y283
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Cat
Felis silvestris
Mouse
Mus musculus
Q62312
592
67103
Y306
V
A
V
K
I
F
P
Y
E
E
Y
S
S
W
K
Rat
Rattus norvegicus
P38438
567
64223
Y281
V
A
V
K
I
F
P
Y
E
E
Y
S
S
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508269
597
68110
Y311
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Chicken
Gallus gallus
Q90999
557
63290
Y271
V
A
V
K
I
F
P
Y
E
E
Y
A
S
W
K
Frog
Xenopus laevis
P27041
511
57917
Q227
V
Q
D
K
Q
S
W
Q
C
E
K
E
I
F
T
Zebra Danio
Brachydanio rerio
NP_878275
556
63419
F267
E
T
V
A
V
K
I
F
P
Y
E
E
Y
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P50488
744
84391
N341
L
V
A
V
K
K
L
N
E
F
Q
K
A
S
F
Sea Urchin
Strong. purpuratus
XP_001184520
615
68501
E300
V
A
V
K
V
F
L
E
Y
D
S
A
S
W
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94
98.9
89.4
N.A.
88.1
91.5
N.A.
74.5
74.9
34
66.8
N.A.
N.A.
N.A.
25.1
32.3
Protein Similarity:
100
94
99.6
93.5
N.A.
92.9
96.3
N.A.
82
85.1
51.6
79.8
N.A.
N.A.
N.A.
42.2
49.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
20
6.6
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
26.6
20
N.A.
N.A.
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
75
9
9
0
0
0
0
0
0
0
59
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
9
75
75
9
17
0
0
0
% E
% Phe:
0
0
0
0
0
75
0
9
0
9
0
0
0
9
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
67
0
9
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
84
9
17
0
0
0
0
9
9
0
0
67
% K
% Leu:
9
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
67
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
9
0
0
9
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
9
17
75
9
9
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
84
9
84
9
17
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
75
0
% W
% Tyr:
0
0
0
0
0
0
0
67
9
9
67
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _